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Microbial-derived peptides Microorganisms, particularly probiotics, play a critical role in enhancing human health by improving nutrient absorption, synthesizing essential vitamins, and producing antimicrobial metabolites that protect against pathogenic organisms

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Thus, the pathogenesis of PND involves mechanisms that extend far beyond the realm of anesthetic management

There are other small molecules of natural origin such asnaringin, apigenin, luteolin, curcumin, genistein etc., known to have moderate effects on DNA methylation [144,145,146]

Magnesium application helps maintain the homeostasis of photosynthate allocation between source and sink tissues and is reported to reduce membrane peroxidation levels by activating antioxidative mechanisms (Senbayram et al., 2015)