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When glutathione and acetaldehyde get bound up together, these glutathione-acetaldehyde "conjugates" reduce glutathione antioxidant activity

Jung HS, Chang Y, Kwon MJ, Sung E, Yun KE, Cho YK, et al

Bottom line: For the best results, take glutathione in the morning and NAC on an empty stomach, ensuring you stay consistent with your daily timing
Kumar S, Mishra A, Pandey AK

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