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Abstract Pregnant women in resource-poor areas are at risk of multiple micronutrient deficiencies, and indicators of low vitamin B-12 status have been associated with adverse pregnancy outcomes, including anemia, low birth weight, and intrauterine growth retardation

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When designing combination protocols, researchers should consider potential interactions, adjust doses appropriately (often using lower doses of each compound), and use enhanced safety monitoring

Individuals with a history of severe allergic reactions to injectable vitamins should be monitored closely or offered alternatives per clinician judgment