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This results in shorter times needed for diffusion

This is largely due to the unique biological and clinical characteristics of GB, including dynamic evaluation of the tumor, its highly heterogeneous tumor microenvironment, and poor drug penetration through BBB, as illustrated in Figure 3
Effects of tamoxifen in relation to breast cancer

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108 The AD brain is characterized by abnormal neuronal copper distribution, with accumulation of copper in amyloid plaques and deficiency in the cells