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As observed, the trend line for the CON was consistently approximately twofolds higher than the corresponding SZ and BP trend line when considering total GSH level over the entire age distribution

However, during increased electron flux, superoxide production may reach a critical threshold, which may allow trafficking of superoxide anions through the mitochondrial transition pore into the cytosol, in which further damage and/or the activation of additional ROS sources may occur

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18 A more comprehensive lipid test, such as the NMR LipoProfile , 6 allows for assessment of the size and density of LDL particles, a feature that increases the prognostic value and sets these advanced tests apart from conventional lipid tests