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Description
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Clinical manifestations include acute pain crises, hemolytic anemia, and multi-organ dysfunction, imposing substantial morbidity and mortality challenges
However, treatment with pan-caspase inhibitor z-VAD-fmk almost completely blocked apoptosis and caspase-3/7 activity, indicating that apoptosis induced by chaetocin and TRAIL was caspase-dependent (Fig
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The reviewer XW declared a shared parent affiliation with the authors to the handling editor at the time of review
