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It has been found to inhibit glucose-6-phosphate dehydrogenase and the pentose phosphate pathway in human and mouse endometrial stromal cells and human breast cancer cells (206, 207), and to increase oxidative phosphorylation in cumulus cells of aged infertile patients and in liver mitochondria of developing rats (208, 209)

This is often seen in children and teenagers

10.1021/acs.chemrev.8b00460 72 MathaiJ

In survivors of ARDS, this impaired regenerative capacity manifests as pulmonary fibrosis, characterized by reduced lung compliance and chronic respiratory dysfunction
