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A pivotal RCT in 116 cannabis-dependent adolescents found that NAC (1,200 mg twice daily) more than doubled the odds of a negative urine cannabinoid test compared to placebo (OR 2.4, 95% CI 1.1-5.2) (Gray et al., Am J Psychiatry, 2012) [76]

This synthetic pentapeptide is thought to operate in a manner akin to Growth Hormone Releasing Peptides (GHRPs) and may simulate the natural action of the hunger hormone, ghrelin

In the realm of natural compounds, ellagic acid alleviates glucosamine-sulfate-induced ulcerative colitis in mice by modulating gut microbiota and inhibiting ferroptosis [304]

doi: 10.1038/s41598-018-32860-x
