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In diabetic rats, gsh deficiency was found to contribute to impaired antioxidant defense mechanisms and increased inflammation

doi: 10.1371/journal.pone.0070760 23 CollinsDWGudisevaHVTrachtmanBTJerrehianMGorryTMerrittWTet al

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Advanced glycation end-products induce apoptosis of vascular smooth muscle cells: A mechanism for vascular calcification

Effects of exogenous MG and NaHS on non-enzymatic antioxidants, MG, and H 2 S contents and glyoxalase system enzymes Compared with control, exposure to Cd increased the contents of GSH, GSSG, and DHA by 28.24, 41.80, and 36.40%, respectively, but decreased the AsA content and the ratios of GSH/GSSG and AsA/DHA by 19.23, 9.97, and 40.44%, respectively (Fig