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Protein denitrosylation: enzymatic mechanisms and cellular functions
In patients with G6DP-deficiency, hemochromatosis, history of kidney stones or chronic kidney disease, or if blood sugar cannot be determined with reliable devices, vitamin C should not be used in higher dosages
Early clinical data revealed heterogeneous [ 18 F] FSPG uptake across tumors and patients, supporting its use in both patient selection and intra-tumor targeting [287]
However, it differs from other forms of PCD in that ferroptosis is based on divalent iron and leads to cell death by promoting lethal accumulation of intracellular lipid peroxides [12]
