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Retinoic acid and TGF- signalling cooperate to overcome MYCN-induced retinoid resistance

Drug Delivery and Translational Research

It is available only as a compounded preparation through 503A/503B pharmacies under valid prescription

It is most often based on the clinical symptoms together with laboratory assessment (low serum vitamin B 12 level and elevated serum homocysteine or methylmalonic acid level) and the response to treatment to make definitive diagnosis
