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Proteolytic stability is often given as an explanation why BPC-157 was under investigation in several ways of administration in animal researches, and why this compound is often mentioned as resistant to degradation in acidic environment, where other peptides decompose easily

Adv Sci 2021, 8: e2102079

Ryanodine receptor leak mediated by caspase-8 activation leads to left ventricular injury after myocardial ischemia-reperfusion

Lutgens E, Atzler D, Dring Y, Duchene J, Steffens S, Weber C

Furthermore, we showed the ectopic MCJ overexpression reversed the improved mitochondrial damage resulting from HIF2 downregulation, as evidenced by electron microscope, ATP level, GSSG/GSH ratio, MitoSOX, and DHE staining