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Variations in the COX-2 gene can be implicated in oxidative stress-related conditions such as cancer, cardiovascular diseases, and neurodegenerative disorders

doi: 10.1007/s12640-017-9835-5 142 TaeneAKhalili-TanhaGEsmaeiliAMobasheriLKooshkakiOJafariSet al

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10.1016/j.ijbiomac.2024.138526 179 VaranasiS

Corroborating these findings, both FTH and FTL overexpression have also been implicated in chemotherapy resistance across various tumor types and chemotherapeutic agents (reviewed in ref
