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Another promising approach involves gold-coated iron oxide nanoparticles functionalized with folic acid for targeted delivery to cancer cells [116]
However, in contrast to Wu and Deng [76], apoptosis was mitigated, as evidenced by decreased levels of Caspase3 and Bax, alongside increased expression of the antiapoptotic marker Bcl2 [84]
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For each section, five random non-overlapping high-power fields (400 magnification) were selected for quantitative assessment of apoptotic markers (caspase-3, Bax, and Bcl-2) and neuronal integrity (Nissl staining)
