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For autoimmune applications, cycling also provides opportunities to assess disease activity off peptide and determine whether improvements are sustained

This can lead to 1-2 week "out of stock" periods that can be frustrating for researchers who haven't planned ahead

On day 6, after the escape platform was removed, spatial memory was evaluated

It's most commonly used as a diluent for reconstituting lyophilised peptides prior to in-vitro study, and while it might seem like a minor detail compared to the peptide itself, using the correct diluent, and understanding its properties, has a direct effect on sample stability and experimental reliability

It is thought to act as a feedback signal generated after tissue injury and also functions as a potent antioxidant