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The up-regulated gene list contained a number of glutathione depletionresponsive genes reported previously, such as Trib3, Srxn1, Myc, Asns, Igfbp1, Txnrd1, or Hmox1, suggesting that these genes are robust mRNA biomarkers for evaluating hepatic glutathione depletion
It contains bioactive compounds with antibacterial and anti-carcinogenic properties, aiding in the prevention of liver cirrhosis and reduction of blood cholesterol levels (6)
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Nevertheless, the protein products of only two genes, GGT1 and GGT5, the latter of which is the approved gene symbol for GGT-rel, were found to function as enzymes
