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It has also been reported that ROS is a critical trigger of cyclooxygenase-2mediated macrophage differentiation from monocytes (108)
doi: 10.3389/fphar.2020.01225
doi:10.1038/nchembio.1204
These types of treatments provide only symptomatic relief, and effective targeting for PD has lagged behind other disease areas, due to drug delivery challenges caused by the bloodbrain barrier (BBB)
