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The clinical pictures of vitamin B12 allergy caused by type 1 hypersensitivity that have been revealed with basophile histamine release test and skin prick tests as we have performed in our patient.10 We did not perform basophile histamine release test or specific IgE determination to indicate type 1 hypersensitivity reaction because of positive SPT results of both types of cobalamin preparation

First, the post incorrectly implies that the risk is mainly due to rapid intravenous administration of methylcobalamin itself, whereas the actual mechanism is related to marrow response after correction of severe deficiency

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