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It has been demonstrated that endonuclease inhibition decreases cell lethality (69), suggesting that DNA fragmentation has a permissive role in APAP liver toxicity

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Thus, it is generally accepted that the neurotoxicity of CPZ is mainly induced by a disturbed mitochondrial function and energy metabolism (Kipp et al., 2009), although whether these consequences are a direct result of copper chelation remains unclear, as copper supplementation has a limited ability to reduce CPZ toxicity (Carlton, 1967)

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The label on your B12/MIC vial will always display your prescribed dose