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Front Microbiol 12:652980

doi: 10.1530/JOE-17-0002
While antibody treatment to combat viral infection has been boosted because of the SARS-CoV-2 pandemic, development in context of pathogenic bacteria is underexplored 6,7

In the present review, we will focus mainly on the signaling cascade of TLR4 because it is believed to be the main sensor of bacterial LPS (Ignacio et al., 2016)

Moreover, gastrointestinal symptoms often reported by individuals with ME/CFS underscore the potential gut-brain axis involvement in disease manifestation [8, 13]
