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KD of Phb2 in epidermal cells using shRNA significantly reduced cell proliferation and impaired the ability to induce hair regeneration from skin organoids posttransplantation (Fig

Under some pathophysiological circumstances, endothelium-derived vasoconstricting factors, such as ET-1, AT-II, urotensin II, superoxide anions, vasoconstrictor prostaglandins and thromboxane A 2 , can be released and contribute to the paradoxical vasoconstrictor effects

This results in blurred or distorted vision