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When the vagus nerve is affected by head trauma, gut motility can become erratic, resulting in symptoms such as constipation, reflux, nausea, or bloating (13)

Scopes of nature-derived compounds in modulating Nrf2/Keap1/ARE axis It has already been discussed that for chemotherapeutic activities, Nrf2 needs to be inhibited while to prevent cancer initiation and recurrence, Nrf2 cascade needs to be activated

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The nuclear translocation of DrP1 increases mitochondrial fission and the inhibition of DrP1 nuclear translocation by melatonin results in suppression of mitochondrial fission [108,109,110,111,112]