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Secondary outcomes The secondary outcomes are as follows: type 2 diabetes, glucose, HbA1c, insulin, lipid profile (LDL-cholesterol, HDL-cholesterol, triglycerides and apolipoprotein B), systolic blood pressure, diastolic blood pressure, and body mass index (BMI), which are well-established risk factors for CVD in clinical practice, or recently identified to be related to CVD in MR, such as apolipoprotein B [30, 31]

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Focus on eating a balanced diet rich in essential vitamins and minerals like iron, zinc, and biotin

doi: 10.1038/s41598-020-64648-3 153 PolsinelliG

Conclusions Several components of the IGF signaling axis, such as IGF-1, IGF-2 and IGF-1R, are dysregulated during HCV-related human HCC