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The AHBA is based on 3702 spatially distinct samples from six post-mortem brains (age = 42.50 13.38 years

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Study highlights importance of careful medication management to avoid druginduced Parkinsonism

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Among non-invasive biomarkers, cytokeratin-18 (CK-18) fragments remain one of the most extensively studied indicators of hepatocyte apoptosis, demonstrating moderate diagnostic accuracy for differentiating MASH from simple steatosis [78]

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1G and S2A), indicating an impact on mitochondrial metabolism

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Kento Fukuoka provided technical assistance

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