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NO is constitutively produced within the endothelium by eNOS and it is thought to freely diffuse into smooth muscle cells, where NO binds to the Fe 2+ -heme center of a soluble guanylyl cyclase leading to vasodilation
Nonetheless, diagnosis and subsequent treatment of SLE have been hampered due to heterogenic clinicopathological presentation of the disease (1, 4, 7)
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[DOI] [PubMed] [Google Scholar] 101.Mesdaghinia E., Rahavi A., Bahmani F., Sharifi N., Asemi Z
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