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Using macrophages, Lin et al
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The Vyleesi label and Phase 3 trial design use a 45-minute interval before sexual activity
Cell-based assays have shown colocalization between PLC isoforms and activators, but it is not clear whether these interactions also lead to increased membrane affinity (Illenberger et al., 2003b
Except for 12 HCV lineages which segregated into six transmission clusters (a pair each for GT1a, GT1b, GT2, GT2a, GT3a and GT4a), polyphyletic patterns were found suggesting multiple and old introductions of the different HCV subtypes in this population (Fig
