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This minor change not only affects the protonation of the chromophore leading to pronounced stabilization of the anionic form of the chromophore (Elsliger et al., E from 280 mV for roGFP2 to 238 mV for roGFP2-iL is lower than the shift for roGFP1-iL which at 229 mV is 62 mV less negative than its parent roGFP1

Investigations over the past 15 years have revealed the importance of the mammalian TrxR1 system in redox signaling

doi:10.3945/an.117.015628

Tania Dempsey: Sensitivity to Salicylates in Mast Cell Activation Disease