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J Clin Endocrinol Metab 98(3):10311039

Studies have found that the Tc9 subset (IL-9-secreting CD8 + T cells) reduces its own lipid peroxidation and ferroptosis by enhancing fatty acid oxidation via the IL-9/STAT3 signaling axis, allowing it to survive longer in the TME and exhibit stronger anti-tumor capabilities (143)

The oily skin is characterized by excessive sebum production by the sebaceous glands , i.e., hyperseborrhea

Notably, BDNF levels fluctuate with the estrous cycle and estrogen administration can increase the expression of BDNF in the PFC and hippocampus 6366