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doi: 10.1093/jac/dkl486 175 SchoemanJFvan RensburgAJLaubscherJASpringerP

Signs of B12 deficiency include: Yellow tinge to skin Dizziness Rapid heartbeat Mouth ulcers Blurred vision Swollen, inflamed tongue (glossitis) Fatigue or weakness Irritability, depression, and other mood changes Pins and needles sensation in hands and feet Memory loss Behavioral changes For mild deficiencies, vitamin supplements and fortified foods can often help restore adequate B12 levels, but sometimes, a vitamin B12 injection is a better option

the 1 mg arm is the lowest measured human pharmacologic activity: Frias Lancet 2018

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