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doi: 10.1186/s12915-025-02154-6 16 JiangXStockwellBRConradM

doi: 10.1111/j.1572-0241.2000.03368.x

However, repeated or vigorous shaking can physically break the peptide bonds, a process called mechanical shearing

456,457 The ATF6 pathway The third arm of the UPR is perhaps also the least complex, as only one proteinthe transcription factor ATF6takes on both the sensor and effector roles
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