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Downstream tissue effects persist substantially longer

Kolovrat et al., 2020) can be foreseen

Schwann cells are responsible for production of ECM, neurotrophic factors, cell adhesion molecules, and other molecules supporting nerve regeneration and providing a favorable environment for cells in tissue (Rasband and Peles, 2015)

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Sterile water has no preservative, so once the vial is punctured, bacteria can grow