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(1990), Aebi (1984), and Ellman (1959), respectively

Over 86% of respondents considered the nasal spray to be comfortable and easy to administer

PROT: Struc Func Bioinfor 57:799803, 2004

Abstract Background Parkinson's disease is a neurodegenerative disorder characterized pathologically by the loss of nigrostriatal dopamine neurons that project from the substantia nigra in the midbrain to the putamen and caudate nuclei, leading to the clinical features of bradykinesia, rigidity, and rest tremor

They are molecularly intermediate between small molecules and macromolecules, but have sufficient biochemical and therapeutic differences