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Description
Eight more mutations (H18D, H21N, R167N, K168A, D171S, K172R, E174S, and I179T) were introduced at binding site 1 on the molecule to prevent PEGylation and to increase the affinity for the receptor at this site
It is entirely valid to feel frustrated by a medical system that often struggles to understand or treat these invisible illnesses

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Chhabra, Y

[DOI] [PMC free article] [PubMed] [Google Scholar] 258.Smith SP
