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Some drugs undergo metabolism to produce toxic metabolites that are carcinogenic or mutagenic

In some embodiments, the otic formulations or compositions disclosed herein also contain preservatives, cosolvents, suspending agents, viscosity enhancing agents, ionic-strength and osmolality adjustors and other excipients in addition to buffering agents

While exposure to cadmium, lead, and mercury adversely affects semen quality (139)

Carfilzomib has shown similar biochemical benefits in preclinical HCU models, although its long-term safety remains yet to be fully elucidated (82)

In this way, an RP can ensure that an assertion is coming from the intended IdP or that an attribute bundle is coming from the intended CSP