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Seven relevant studies were included in the meta-analysis, which demonstrated that the combination of gabapentin and opioids effectively reduced pain intensity compared to opioids alone [69]
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IGF-1 binding proteins (IGFBPs) are hypothesized to have a role in glucose metabolism, with IGFBP-1 acutely regulating glucose levels through its effects on free IGF-I (24)

Of the participants in the CT group, one man experienced mild gingival bleeding and one woman had premature menstruation during the fasting period
