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The nanoparticle-loaded edaravone showed reduced edema as compared to free edaravone treated group, significantly improved neurological function, and reduced the production and release of interleukin and tumor necrosis factor, which was considered beneficial to protect healthy brain tissue and other organs, and conducive to the recovery and healing [275]

Inject the solvent into the peptide vial along the inside glass wall rather than directly onto the lyophilized powder, then swirl gently in a circular motion until the powder dissolves completely do not shake, vortex, or invert vigorously, as mechanical agitation can denature peptide secondary structure

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Altuntas EE, Durmus K, Bora A, Turgut NH, Terzi H, Kutluhan A (2020) Examination of ototoxicity induced by imatinib, being a tyrosine kinase inhibitor: an experimental study