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Cocaine binds with high affinity to the norepinephrine transporter (NET) on the presynaptic nerve terminal (Kd 0.3 M), acting as a transmembrane physical plug that inhibits reuptake of norepinephrine

Glutamine uptake via ASCT2 is sodium-dependent, meaning the transport is coupled to the movement of sodium ions into the cell, which helps drive the uptake of glutamine against its concentration gradient

Br J Cancer 114(1):103-9, 2016

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doi: 10.1111/jpn.13259 41 DaviesJHeebHGarimellaRTempletonKPinsonDTawfikO
