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Research has identified potential interactions with NMDA receptor modulation and MAPK signalling pathways, with data suggesting structural homology to glucocorticoid-induced leucine zipper (GILZ) a protein involved in anti-inflammatory and immune-regulatory signalling via the ERK pathway

Ongoing clinical trials and future research directions There are currently no registered clinical trials specifically focusing on DSIP

prove the contribution of vitamin B1 and cobalamin supplementation to the mitigation of neuron apoptosis and nerve injury in cerebral palsy (83)

However, most research connecting acupuncture and hypothyroidism consists of individual case studies, so larger-scale studies are needed to confirm this correlation