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Once p53 is freed, it moves out of the nucleus toward the mitochondria and sets off the intrinsic apoptosis pathway (a caspase-driven self-destruct program)
doi: 10.1016/S0065-2164(10)72002-5 5 GenantHKMallJCWagonfeldJBHorstJVLanziLH
It plays a crucial role in maintaining the integrity and strength of tissues, supporting connective structures such as tendons, skin, and teeth, and stabilizing cellular frameworks within body tissues [21]
Pain 18 , 4253 (2017)
This is an in vivo, systemic treatment, administered intravenously in a single dose
