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In terms of mechanism of action, succinate derivatives are responsible for enhancing the flow of electrons between MEC I and MEC II, as well as directly interacting with the respiratory chain to raise the sensitivity of the process to malonate (Demchenko et al., 2008)

Cells were centrifuged at 151 g for 10 min at 4C to remove supernatant

Sample loading buffer and buffer A consisted of a mixture of 98.9% water, 1% methanol, and 0.1% formic acid (v/v)

Besides producing light sedation without respiratory depression, dexmedetomidine has anxiolytic and sympatholytic properties that reduce autonomic hyperactivity, qualities that support its use in AWS

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