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We also conducted the gene-gene network analysis inspired by STRING results, and similar variant analysis was expanded to genes interacted with each of FMO3 (Additional file 1: Figure S1), PYROXD2 (Additional file 1: Figure S2) and DMGDH (Additional file 1: Figure S3)

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This ability will either increase enzymatic activity or have inhibitory action on enzymes depending on how proteins can interact with polyphenols during digestion

Keywords: anti-obesity, extracts, natural products, purple tea, weight loss Introduction and background Obesity has emerged as a critical global health challenge, characterized by its complex interplay with numerous comorbidities such as type 2 diabetes, cardiovascular diseases, and certain malignancies