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Known for dose-dependent responses in controlled settings

Furthermore, this accumulation was observed as early as 2 months of age and was maintained throughout aging, which may imply that impaired TDP-43 proteostasis is underlying the social and cognitive phenotypes observed in female TDP-43 K408R animals

The examination included collecting an anamnesis (including the use of urate-lowering drugs), examination, anthropometric data (height, weight, BMI), determination of the level of uricemia, ultrasound (GE Voluson E10 device, Austria) of the foot joints to identify deposits of MSU crystals

Biotech 12:39

J Cell Physiol (2019) 234(7):1086876