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Without dual-energy X-ray absorptiometry or imaging, we cannot say with precision how much of the weight change was fat versus water versus lean tissue

NNMT is downregulated in pheochromocytoma and paraganglioma (PCPG) Pheochromocytoma and paragangliomas (PCPGs) are rare and unique tumors originating from the neural crest-derived chromaffin cells in the adrenal medulla or paraganglia [113]

This finding is encouraging, as it suggests 5-Amino-1MQ works by altering metabolic function rather than suppressing hunger