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Since the benefits of hydroxocobalamin over cyanocobalamin have become more apparent, the former has become the main substance used in B12 injections in Europe

The development of neuronal senescence can be also linked to oxidative damage, as it was observed in rodents treated with DCTX (Moruno-Manchon et al., 2016)

In a prospective case-control study, increased plasma cysteine levels were positively correlated with an increased risk of breast cancer

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Translational limitations Although the phytochemical-mediated uPA/uPAR inhibition shows strong compelling in vitro and preclinical evidence, with a number of pharmacological challenges, there is limited translation of the inhibition into clinical benefit