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APAP and erastin also induced significant cytotoxicity in Hepa RG, with IC 50 of 9.8 mM and 39 M, respectively (Fig

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The co-crystallized fragments found in sub-pockets A-C and the protein were used as input for the SZMAP, Gameplan, and vBrood applications and visualization in MOE

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Discovery of LWY713 as a potent and selective FLT3 PROTAC degrader with in vivo activity against acute myeloid leukemia

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Ojo AO, de Smidt O

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doi: 10.2147/IJN.S50683

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