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But not all of them

Conclusion: Our findings suggest that melatonin effectively reduces oxidative stress

As research continues and hopefully expands to include detailed human pharmacokinetic studies and well-controlled trials, the evidence base for optimal dosing will strengthen

BMJ have an article "Guide to ethical approval" Search for "BMJ Guide to Ethical Approval" to find it

The 50 mg vial is reconstituted with 2 mL of bacteriostatic water, yielding a 25 mg/mL concentration (0.25 mg per unit on a 1 mL insulin syringe)