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Amiodarone , a drug used to treat irregular heartbeat, was given to a group of rats along with guarana extract

This can trigger downstream pathways leading to apoptosis (programmed cell death), neuronal degeneration, and, ultimately, neurodegenerative diseases like Parkinsons and Alzheimers disease (AD) (Roussel et al., 2013)

Perfluorooctane sulfonate induces apoptosis in lung cancer A549 cells through reactive oxygen species-mediated mitochondrion-dependent pathway

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