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This is the direct-repair option, and the one researchers reach for when they want to skip the pituitary step

Semin Arthritis Rheum 2022

Sixth, MSCs immunosuppressive effects are linked to their secretory profile and stemness-related pathways

doi:10.1056/NEJMoa2101544 25
mTORC2 remains unaffected and responds by upregulating Akt, driving signals through the inhibited mTORC1
