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GBMs demonstrate remarkable metabolic plasticity, relying on glucose metabolism while adapting to alternative carbon sources under stress

Formation of mitochondrial phospholipid adducts by nephrotoxic cysteine conjugate metabolites
In addition, GPx-4 depletion in cell culture also promotes cell death by apoptotic mechanisms that could not be alleviated with water-soluble antioxidants, confirming that intracellularly GPx-4 mainly prevents lipid peroxidation, essentially antagonizing the actions of lipoxygenases and cycloogenase

(1998): The effect of stress on homeostasis in JCR:LA-cp rats: the role of nitric oxide

Another study showed that fluoxetine treatment in ewes during the last month of pregnancy reduced placental nodule growth, shortened the gestational period by 4.5 days, and decreased the birth weight of lambs following exposure in utero
