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[14] In 1986, FDA substantially revised and expanded these cGMP regulations to better ensure the production of safe and sanitary foods
For the research context it expanded the perspective from pure longevity to specific clinical indications , especially neurodegenerative diseases, where mitochondrial dysfunction and NAD+ deficit play a central role
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High B12 is not usually dangerous on its own, but may point to issues like liver disease, kidney dysfunction, or blood cancers
